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Gastrointestinal worms
Gastrointestinal worms are hugely important, much studied macroparasites which are relatively easy to work with. The species we use have long been studied in the laboratory as model GI nematodes and it is relatively easy to obtain fresh parasite isolates from the field. Rats and mice are their natural host. We use a range of GI nematodes because the contrasting natural histories capture different features of the range of GI nematodes which cause problems for humans and domestic animals. In vivo model systems we use include: Strongyloides ratti, S.venezulensis, Heligomosomoides polygyrus, and Nippostrongylus brasiliensis.
